CXCL1 and prostate adenocarcinoma: Among them, IL-1β, IL-6, and CXCL1 have been reported to be factors of immune suppressive SASP that attract myeloid-derived suppressor cells (MDSCs) to inhibit cytotoxic NK and T cell responses in prostate adenocarcinoma (Garcia et al., 2014; Toso et al., 2014).