For instance, the presence of oligoclonal bands in the CSF and typical brain lesions involving periventricular or juxtacortical areas suggests MS as the most likely disease cause, while absence of oligoclonal bands, very high cellularity in CSF (especially neutrophils or eosinophils) combined with non-specific or normal brain MRI findings could indicate AQP4+NMOSD. The gene discussed is AQP4; the disease is myeloid sarcoma.