MED22 and hepatocellular carcinoma: Finally, four prognosis-related LMAGs (mediator complex protein 22 (MED22), mediator complex protein 7 (MED7), TXNRD1, and lecithin−cholesterol acyltransferase (LCAT)) were identified, and the risk score was calculated (risk score = 0.3402 × ExpMED22 + 0.4330 × ExpMED7+ 0.2259 × ExpTXNRD1 - 0.1748 × ExpLCAT) for each HCC sample (Figures 4A,B).