The following variables were included in the univariate Cox regression analysis having as outcome occurrence of significant fibrosis stage (≥2) after LT (fibrosis evaluated by both concordant Fibroscan >8.1 kPa and FIB-4 >1.45): genotype CC of CYP3A5 gene; genotypes TT and CC of TBX21 gene; age of recipient and of the donor; presence of post-LT diabetes mellitus; HCV etiology of liver cirrhosis at LT; use of TAC, SRL and MMF; NLR and PLR values as well as steatosis grade evaluated by CAP. The gene discussed is TBX21; the disease is steatosis.