It’s reported that ARID1A depletion accelerates EMT, increases cancer stemness and promotes migration, invasion and angiogenesis in various cancers by reducing the chromatin accessibility of target genes or influencing the post-transcriptional modification process (Wilson et al., 2019; Luo et al., 2020; Wang et al., 2020; Tomihara et al., 2021). Here, ARID1A is linked to cancer.