Thus, in seeking to assess the TREML4 expression profile throughout the progress of ischemic heart disease, our study aimed to investigate relationships between TREML4 mRNA expression in blood leukocytes and its polymorphisms (rs2503495 and rs2803496) in asymptomatic patients and in patients who developed left ventricular (LV) dysfunction after MI. Here, TREML4 is linked to coronary artery disorder.