The results from the Step3 sensitivity analysis using CRP ≥ 5 mg/L as cut-off were essentially the same as with CRP ≥ 3 mg/L (RA; HR = 1.23 (0.99, 1.55), p = 0.062, CRP; HR = 1.58 (1.47, 1.70), p < 0.001). The gene discussed is CRP; the disease is rheumatoid arthritis.