As mentioned previously, Striatin 4 was recruited by SV40 ST to the Striatin Interacting Phosphatase and Kinase (STRIPAK) complex that redirects PP2A function toward the dephosphorylation of MAP4K4, leading to the activation of YAP1 and the inactivation of Hippo tumor-suppressive function (44). This evidence concerns the gene YAP1 and neoplasm.