Lastly, our meta-analyses also found marginal evidence for an association between severe COVID-19 and pLoFs (M1) in RILPL1 (OR: 20.2, 95% CI: 5.8–70.7, p = 2.42x10-6), a gene that, like MARK1, is associated with microtubule formation and ciliopathy [34]. The gene discussed is RILPL1; the disease is ciliopathy.