IL18 and colorectal cancer: On the other hand, some authors demonstrated that NLRP3 inflammasome could also have an anti‐tumorigenic role: In divergence with the role of NLRP3 inflammasome in colorectal cancer cited above, Dupaul‐Chicoine et al. (2015) stated that IL‐18 release through NLRP3 pathway restrains colorectal cancer metastatic growth in liver by the increase of natural killer cell tumoricidal activity.