CEACAM5 and nutritional deficiency disease: There was no significant variability in ECOG-PS, gender, age, number of metastatic sites, PD-L1 expression status, smoking and drinking history, primary tumor site, histological differentiation, surgery history, presence of liver metastasis, carbohydrate antigen 19–9 (CA19-9), carcinoembryonic antigen (CEA), and anti-PD-1 type and treatment line or type, risk of malnutrition (Table 1).Of the 237 patients, 30.85% patients in the PLR < 139.41 group demonstrated an objective response (1 CR and 28 PR).