ABCA7 and Alzheimer disease: ABCA7 is implicated in AD pathology through amyloid precursor protein (APP) endocytosis, impaired amyloid‐beta (Aβ) clearance and, although not fully elucidated, lipid metabolism dysregulation via sterol regulatory element‐binding protein 2 (SREBP2) (Aikawa et al., 2018).