CD4 and gastric cancer: In a study conducted by Peker et al. on the effect of immunonutrition on TILs in gastric cancers, there was no significant difference between CD 4 and CD 8 rates in both the patients given immunonutrition and those not given immunonutrition, and the CD4/CD 8 ratio was found to be significantly lower in the immunonutrition group [14].