This observation was similar in three independent MEN1 cohorts from France (RR 2.33; p=0.03), the United States (RR 2.40; p=0.11), and Australia (Tasmania) (RR 2.31; p=0.22), although only one of these comparisons was significant, likely due to the small numbers of breast cancer patients in those MEN1 registries. The gene discussed is MEN1; the disease is breast cancer.