However, only 3 of them have been attributed to pathogenesis and clinical consequence, NM_138715.3 (MSR1): c.520G>T (p.Asp174Tyr) and c.877C>T (p.Arg293Ter) in prostate cancer (65); and c.760C>G (p.Leu254Val) specifically related to Barrett oesophagus and oesophageal adenocarcinoma (66). This evidence concerns the gene MSR1 and Familial prostate cancer.