CD45.1+ AF+ macrophages expressed the CD206 but not the TIM-4 marker 30 days after grafting (Figure 4E), suggesting that CD206+TIM-4- AF+ macrophages can derive from post-natal hematopoiesis, mainly from bone marrow monocytes in our experimental conditions, contrary to CD206+TIM-4+ AF+ macrophages. The gene discussed is MRC1; the disease is atrial fibrillation.