qRT-PCR results showed that the expression level of HK3 in PBMCs of GD (n=30) and HT patients (n=30) was significantly higher than that of controls (n=30) (P=0.019 and 0.045, respectively), while there was no abnormal expression of HK1 and HK2 in PBMCs of AITD patients (P>0.05) (Figures 6B, C). This evidence concerns the gene HK3 and hematocrit.