CSF3 and Stroke: For example, Shuxuening injection improves I/R injury mainly through anti-inflammatory and antioxidant effects in the acute phase of stroke mice, promotes the recovery of neurological function by inhibiting G-CSF-mediated granulocyte adhesion and diapedesis pathway in the subacute phase, and restores post-stroke cognitive and motor deficits via regulating BDNF-mediated Neurotrophin/Trk signaling pathway in the recovery phase (56–58).