On one hand, interleukin-8 (IL-8) secreted after myocardial ischemia recruits bone marrow-derived mesenchymal stromal cells (MSCs) to the sites of degenerated tissue of myocardium by interacting with CXCR1 overexpressed on MSCs, thereby reducing the ischemic area and improving cardiac function (61). The gene discussed is CXCR1; the disease is myocardial ischemia.