On the other hand, given the importance of inflammatory cytokines in the pathogenesis of SjS, techniques with a more functional approach based on the measurement of cell expression of different immune-related molecules such as IFN, and its correlation with the presence of certain auto-antibodies, are being studied in other rheumatic autoimmune diseases with interesting results related to their possible role in the autoimmunity response in those patients (100). The gene discussed is IFNA1; the disease is Schwartz-Jampel syndrome.