In general, CD8-predominant AITL had characteristic AITL histological features, with effaced lymph node architecture (6/6, 100%, Figure 1A) in a diffuse growth pattern (6/6, 100%, Figure 1B) harboring arborizing proliferation of HEVs (6/6, 100%, Figure 1C). This evidence concerns the gene CD8A and angioimmunoblastic T-cell lymphoma.