Comparative analysis identified 36 genes in this panel with significant differential expression between CD8-predominant AITL and common AITL through the linear model fit with p-value correction (Padj < 0.05 and log2fc > 1), of which 20 genes were upregulated and 16 genes were downregulated in CD8-predominant AITLs (Figure 5A). This evidence concerns the gene CD8A and angioimmunoblastic T-cell lymphoma.