AHR and polycystic ovary syndrome: Moreover, some studies have pointed out that environmental endocrine disruptors such as polycyclic aromatic hydrocarbons may affect reproductive endocrine function through the AHR signalling pathway and participate in the occurrence of reproductive endocrine diseases such as polycystic ovary syndrome (PCOS) and postmenopausal osteoporosis (PMO) (Naruse et al., 2002; Vandenberg et al., 2009).