ACE2 and non-small cell lung carcinoma: We also analyzed ACE2 transcript expression in normal lung tissue derived from 32 patients with metastatic NSCLC who participated in the WINTHER clinical trial (Supplemental Table 2)25; as seen in Figure 1(c), their expression was further shifted to the right in the curve, consistent with higher ACE2 expression levels in normal lung tissue from patients with metastatic NSCLC versus that from patients with resectable NSCLC.