It has been found that the extract solution of Ulmi Cortex significantly reduces the production of IL-2 and TNF-α in peritoneal macrophages and synovial membranes for arthritis animal models, (Song et al., 2007), and Cinnamomi Cortex pharmacopuncture has anti-inflammatory effects such as inhibition of ERK1/2 phosphorylation and COX-2, iNOS expression. The gene discussed is MAPK3; the disease is arthritic joint disease.