We investigated genetic correlations between early-onset AN and 62 traits prioritized from six categories based on previous evidence from AN (5,17): psychiatric (i.e., schizophrenia, major depressive disorder), anthropometric (i.e., weight, height), glycemic (i.e., type 2 diabetes, insulin resistance), lipid related (i.e., high-density lipoprotein cholesterol, triglycerides, leptin), reproductive (i.e., age at menarche, age at menopause), and education and intelligence (i.e., IQ, college completion). This evidence concerns the gene LEP and major depressive disorder.