adh5 is the gene encoding GSNOR and is located on the reverse strand of chromosome 4 (4q23 - chr4: 999993567-10000985), and high levels of human epidermal growth factor receptor 2 (HER2) expression in breast tumors are associated with low GSNOR expression and apoptosis protein S-nitrosylation was associated with an increase in (21). This evidence concerns the gene ERBB2 and breast neoplasm.