Compared with that in the control groups, adding NGAL reduced the tube formation of human umbilical vein endothelial cells (HUVECs) in MIA PaCa-2 (RRID: CVCL_0428) and PANC-1 (RRID: CVCL_0480) (two pancreatic cancer cell lines) cells by 69.5% ± 5% and 68% ± 7.5%, respectively (62). This evidence concerns the gene LCN2 and pancreatic neoplasm.