The TCGA and the GTEx database were used to analyze FOXN3 expression in generalized carcinoma on the GEPIA2 online platform, revealing that FOXN3 was down-regulated in Bladder Urothelial Carcinoma (BLCA), Breast invasive carcinoma (BRCA), Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), Colon adenocarcinoma (COAD), etc. In contrast, FOXN3 was up-regulated in Kidney Chromophobe (KICH), Pancreatic adenocarcinoma (PDAC) and Thymoma (YHYM) (Figures 2A, B). Here, FOXN3 is linked to colon adenocarcinoma.