The second signal (rs2265634; Pcorrected= 1.14 × 10−6) is between Diaphanous homolog 1 (DIAPH3), which modulates mTOR signaling and cellular proliferation (Wan et al., 2021), and Tudor domain-containing protein 3 (TDRD3), a chromatin modulator also involved in proliferation (Morettin et al., 2017); it is also close to long non-coding RNA LINC00434. LINC00434 appears to target several genes involved in cancer and autoimmunity (Supplementary Table S4). The gene discussed is MTOR; the disease is cancer.