Interestingly, we found that the expressions of IL6, KRAS, CCL2, IL10, TLR4, STAT3 and PPARG in HF patients were down-regulated compared with healthy samples, while the expressions of JUN, IL1β and CXCL8 were up-regulated in HF samples compared with healthy samples (Figure 3A). This evidence concerns the gene IL1B and hydrops fetalis.