LOXL3 and melanoma: Downregulation of LOXL3 achieved a remarkable inhibitory effect on the migration and invasion of melanoma cells which were observed via transwell assay (Figure 7G–I) and wound healing experiment (Figure 7J–L), while overexpression of LOXL3 could promote the migration and invasion of melanoma cells observed via transwell assay (Figure 8B,C) and wound healing experiment (Figure 8D,E).