On the one hand, CXCL10 secreted by TA-MSCs bind to its cognate receptors CXCR3 presented in cancer cells, and simultaneously, CXCL16 derived from cancer cell bind to CXCR6 on TA-MSCs surface, eventually potentiating the recruitment of TA-MSCs into tumor areas. This evidence concerns the gene CXCR6 and cancer.