VEGFA and aneurysm: Among the included patients, 5 patients received observation, 4 patients received direct laser photocoagulation (around 532 nm green laser, about 200um in the diameter of the light spot around and/or direct to the aneurysm, 100–300 mW for laser power, 0.2 ~ 0.3 s for laser duration, and level III for laser response), and 5 patients underwent anti-VEGF therapy.