By contrast, YUMM1.7 (the parental and non-immunogenic29 counterpart of YUMMER1.7) showed similar tumour growth (Extended Data Fig. 6m) and a similar frequency of intratumoral PD-1+LAG3+TIM3+ CD8+ T cells in both the presence and the absence of nociceptors (not shown). This evidence concerns the gene CD8A and neoplasm.