Although chemoablation of nociceptor neurons with resiniferatoxin (RTX) reduced tumour growth in B16F10-inoculated wild-type mice (Extended Data Fig. 6o), we found that naive OT-I CD8+ T cells enhanced tumour shrinkage when transplanted in RTX-exposed Rag1−/− mice (Fig. 3g). Here, RAG1 is linked to neoplasm.