High MeCP2 expression was associated with better overall survival (OS) in certain forms of cancers (BLCA, CESC, KIRC, MESO, LUAD, SARC, STAD, PAAD and UCEC), and worse OS in cancers (ACC, BRCA, DLBC, KICH, LIHC, LGG, HNSC, PRAD, THCA, UVW, COAD, and LAML), P < 0.05 for all (Fig. 3A). This evidence concerns the gene MECP2 and cancer.