Reduced expression of BLACAT1 in HNSCC; MALAT1, NEAT1 and PVT1 in NPC; FAM201A, PVT1 and LINC00857 in NSCLC; LINC00473, CCAT2and Rpph1 in EC; HOTAIR and LINC00958 in CRC; AFAP1-AS1 and LINC00511 in breast cancer were correlated with radiosensitivity. The gene discussed is PDE10A; the disease is head and neck squamous cell carcinoma.