MYC and neoplasm: To assess the impact of MYC expression on inflammatory signaling in TNBCs, we performed gene set enrichment analysis (GSEA) on RNA sequencing (RNA-seq) data obtained from pre-treatment tumor samples from the TONIC phase II trial (NCT02499367), which evaluated the efficacy of nivolumab after immune induction in TNBC patients (Voorwerk et al.30).