Compared with normal tissues, the RUNX1 expression increased in 15 cancers (bladder, brain, breast, cervical, colorectal, esophageal, gastric, head and neck, kidney, leukemia, lung, lymphoma, myeloma, pancreatic, and sarcoma cancers) and decreased in 7 cancers (breast, leukemia, lung, lymphoma, melanoma, prostate, and sarcoma cancers) (Figure 1A, left panel). The gene discussed is RUNX1; the disease is leukemia.