Several interesting hits were linked to the major type 1 and 1B, middle cluster which bears many similarities to type 1: hypoxia‐inducible factor 1‐alpha (HIF1A), previously associated with aggressive tumor phenotypes, treatment resistance, and poor clinical prognosis (Wigerup et al, 2016); TP63, known to regulate migration, invasion, and in vivo pancreatic tumor growth (Somerville et al, 2018); and snail family transcriptional repressor 1 (SNAI1), involved in EMT induction. This evidence concerns the gene HIF1A and neoplasm.