In adults, many of these genes encode sarcomere and cytoskeletal proteins, whereas in children, cardiomyopathy genes often encode neuromuscular, metabolic, and mitochondrial proteins.1 Pathogenic variants in cardiomyopathy genes primarily trigger 1 of 2 dichotomous cardiac morphologies: hypertrophy (increased ventricular wall thickness and mass with reduced chamber volumes) or dilatation (normal ventricular wall thickness and increased chamber volumes).2 This evidence concerns the gene DNM2 and cardiomyopathy.