In the second in vivo experiment, when the size of the transplanted tumor reached 50mm3, we randomly divided the mice into 3 groups (n = 5): PBS control group (named PBS in short), NC-T control group (named NC-T in short), B7-H3 CAR-T group (named B7-H3 CAR-T in short, injected dose was 5*106CAR + cells per mouse) (Fig. 5G). Here, CD276 is linked to neoplasm.