PLEKHA1 and Charcot-Marie-Tooth disease type 4E: And the other 4 genes have been associated with schizophrenia (MGAT4A [56]), Leigh syndrome (ADI1, OMIM: 256,000), congenital hypomyelinating neuropathy (PLEKHA1, OMIM: 605,253), and ID (PCK2 [64]), respectively.