Some psoriasis loci showed a substantial single-tissue eQTL, primarily in the cardiovascular system (artery coronary: rs240993/KIAA1919, rs9808753/TMEM50B, heart left ventricle: rs11053802/KLRC4, heart left ventricle: rs11053802/KLRK1, rs5063/CLCN6, rs1050414/HLA-B, rs2778031/SPIN1). The gene discussed is SPIN1; the disease is psoriasis.