Moreover, the CXCR3 ligands C-X-C motif chemokine ligand 9 (CXCL9), CXCL10 and CXCL11, which are secreted in response to type I interferon (IFN) and interferon gamma (IFNG) signaling, have been mechanistically implicated in NK cell infiltration of experimental lung adenocarcinomas [39] lymphomas [40] and melanomas [41]. This evidence concerns the gene CXCL9 and melanoma.