IDO2 expression was positively associated with female gender (P = 0.017), multifocality (P = 0.038), ETE (P = 0.020), pT stage (P = 0.019), pN stage (P < 0.001), and 8th AJCC pTNM stage (P < 0.001), but it was not correlated with age, bilateral lesions, maximum tumor size, and coexisting HT (P > 0.05; Fig. 1B). The gene discussed is IDO2; the disease is neoplasm.