In addition, the expressions of DKC1, NSUN5, FLNA and CSE1L were validated by qRT-PCR and IHC, and found that DKC1, CSE1L and NSUN5 were highly expressed and FLNA was underexpressed in CRC tumor tissues, consistent with the data in TCGA database. Here, DKC1 is linked to colorectal carcinoma.