By comparison, we found that only IL-8 had statistical difference in patients without infection (P = 0.0004), only IL-6 had statistical difference in patients with pulmonary bacterial infection (P = 0.0120), and IL-12P70 (P = 0.0046) and INF- γ (P = 0.0279) in patients with pulmonary bacterial and fungal infection had statistical difference (Supplementary Table 1). This evidence concerns the gene IL6 and fungal infectious disease.