There were significant differences in IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-1β, IL-2, TNF-β, IL-17, and IL-22 between the uninfected group and the pulmonary bacterial and fungal infection group (P < 0.05) (Table 2, Fig. 1D–F, Supplementary Fig. 1A–E,G,H). This evidence concerns the gene CXCL8 and fungal infectious disease.