However, when compared individually, the genotypes and alleles of the IL-1β (+3954 C/T, exon 5, rs1143634) polymorphisms were differently distributed (P = 0.03 and P = 0.02, respectively) between APL patients and controls, mainly due to a higher representation of the variant T allele and TT genotype in the APL group (these individual comparisons data are not shown in Table 4). The gene discussed is IL1B; the disease is acute promyelocytic leukemia.