https://doi.org/10.1001/jama.2020.12134): see eFigure 2, eTable 10 (specificity of 79% for plasma p-tau 217), Figure 2A (significant AD overlap vs. non-ADD values of plasma p-tau 217), Figure 1d (significant AD overlap vs. non-ADD values of plasma p-tau 181), Table 2 (significant AD overlap vs. non-ADD values of Plasma p-tau 181- specificities of 67.2% between AD and Frontotemporal Lobar dementia (FTLD) + TDP + FTLD-tau, and specificity of 63.5% between autopsy-confirmed AD and FTLD-tau, and specificity of 62.6% between autopsy-confirmed AD and FTLD + mutation carriers10. The gene discussed is MAPT; the disease is Alzheimer disease.