Two HLA-C2/C2 tumor lines, BJAB (Burkitt-like lymphoma) and HL-60 (AML), displayed significant levels of HLA-C2 as assessed by KIR2DL1-Fc binding, and high rates of killing could be observed in the mismatched setting (figure 4A–C). The gene discussed is KIR2DL1; the disease is acute myeloid leukemia.