The tumour suppressor function of BAP1 is also described in prostate and kidney cancers in which BAP1-dependent deubiquitinase activity stabilizes the tumour suppressor Phosphatase and Tensin homolog (PTEN) and Death Inducer-Obliterator 1 (DIDO1), a protein of the centrosome involved in spindle assembly and correct chromosome segregation [35–37]. The gene discussed is BAP1; the disease is neoplasm.